CN
肿瘤学
Epigenetic multi omics mechanism study on the reduction of renal fibrosis by gen..

N6 methyladenine (m6A) plays an important role in renal physiology and disease progression, but its function and mechanism in renal fibrosis still need to be comprehensively and deeply explored. There...
Hepatology| 浙江大学医学院徐骁教授团队利用多组学技术研究肝细胞癌微环境中DOCK2相关..

肝细胞癌（HCC）是一种恶性疾病。与酪氨酸激酶抑制剂（经典疗法）相比，免疫检查点抑制剂在治疗肝癌方面更有效，尽管其疗效有限。其中一个限制因素是肿瘤浸润淋巴细胞，特别是CD8+ T细胞的功能衰竭。本文的目的是确定...
Xiangya Hospital of Central South University explores a new immunotherapy target..

Although immunocheckpoint block (ICB) therapy has been approved for bladder cancer (BLCA), only a few patients respond to these treatments, so it is urgent to explore combined therapy.

Cell Journal | Study on the Antitumor Effects of Vascular and Hematocyte Immune ..

On May 16, 2023, the Precision Medicine Research and Pediatric Surgery Department of the First Affiliated Hospital of Sun Yat sen University jointly published a paper in Cell Reports Medicine. This st...
树突状细胞（DC）疫苗联合过继性T细胞辅助疗法应用于抗肝癌复发的临床研究

肝癌患者术后五年内复发率高达70%，但目前尚无有效方法预防肝癌复发。肝癌的高复发率是影响患者长期生存的重要因素之一，如何预防肝癌复发已成为肝癌临床诊疗中的一大难题。肿瘤新生抗原是由肿瘤细胞基因突变产生，可...
利用Tissue Cytometry技术筛选和评估PRSS3亚型，以探索其作为潜在肺癌新药靶点的可能性..

随着对参与表型可塑性的RNA异构体的困惑增加，异常的CpG甲基化介导的选择性剪接中断越来越被认为是肿瘤内异质性(ITH)的驱动因素。 蛋白酶3(PRSS3)具有4种亚型，即PRSS3-V1到V4，是一种不可或缺的胰蛋白酶，对肺癌的...
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