Immunosuppression of the tumor microenvironment is the main obstacle to tumor immunotherapy. Interferon stimulating factor (STING) agonists can trigger inflammatory innate immune responses, potentiall...

Kindlin-2 is an important integrin binding protein encoded by the FERMT2 gene, which is highly expressed in organs derived from the mesoderm, including smooth muscles, heart, blood vessels, and bones....

Lung cancer is the leading cause of cancer-related deaths worldwide, resulting in approximately 1.8 million deaths annually, with lung adenocarcinoma (LUAD) being the predominant pathological type. Th...

In melanoma tissue, the proportion of positive cells for genes related to cell death (PRGs) GZMA, GSDMB, NLRP1, IL18, and CHMP4A is lower than in normal skin. Cellular pyroptosis is a new field that a...

In order to explore the origin of tumor stem cells, some studies suggest that they originate from differentiated non stem cells, which acquire stem cell like features after malignant transformation. I...

Worldwide, breast cancer is the main type of cancer for women, accounting for 25% of all cases. It is more common in developed countries. The incidence rate of women is more than 100 times that of men...